In the 1970s, scientists discovered the first incretin hormone, GIP (Glucose-Dependent Insulinotropic Polypeptide), and later identified the second incretin hormone: Glucagon-Like Peptide-1 (GLP-1). GLP-1 is secreted by intestinal L cells in the distal small intestine and proximal colon, encoded by the proglucagon gene, and is a polypeptide...
In the 1970s, scientists discovered the first incretin hormone, GIP (Glucose-Dependent Insulinotropic Polypeptide), and later identified the second incretin hormone: Glucagon-Like Peptide-1 (GLP-1). GLP-1 is secreted by intestinal L cells in the distal small intestine and proximal colon, encoded by the proglucagon gene, and is a polypeptide consisting of 30 amino acids[1-3].
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